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Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors
Cancer is associated with alterations in epigenetic mechanisms such as histone modifications and methylation of DNA, and inhibitors targeting epigenetic mechanisms represent a novel class of anti-cancer drugs. Neuroendocrine tumors (NETs) of the pancreas (PNETs) and bronchus (BNETs), which may have...
Autores principales: | Lines, K E, Stevenson, M, Filippakopoulos, P, Müller, S, Lockstone, H E, Wright, B, Grozinsky-Glasberg, S, Grossman, A B, Knapp, S, Buck, D, Bountra, C, Thakker, R V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523063/ https://www.ncbi.nlm.nih.gov/pubmed/28504695 http://dx.doi.org/10.1038/oncsis.2017.30 |
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