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The zinc-finger transcriptional factor Slug transcriptionally downregulates ERα by recruiting lysine-specific demethylase 1 in human breast cancer

Estrogen receptor α (ERα) is related with epithelial–mesenchymal transition, invasion and metastasis, and serves as an important therapeutic predictor and prognostic factor in breast cancer patients. The triple negative breast cancer (TNBC) is characterized by loss of hormone receptors and human epi...

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Detalles Bibliográficos
Autores principales: Bai, J-W, Chen, M-N, Wei, X-L, Li, Y-Ch, Lin, H-Y, Chen, M, Li, J-W, Du, C-W, Man, K, Zhang, G-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523071/
https://www.ncbi.nlm.nih.gov/pubmed/28481366
http://dx.doi.org/10.1038/oncsis.2017.38