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α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway

Abnormal sialylation due to overexpression of sialyltransferases has been associated with tumorigenesis and tumor progression. Although ST6Gal-I influences cancer persistence and progression by affecting various receptors, the underlying mechanisms and mediators remain largely obscure, especially in...

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Detalles Bibliográficos
Autores principales: Zhao, Y, Wei, A, Zhang, H, Chen, X, Wang, L, Yu, X, Yuan, Q, Zhang, J, Wang, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523073/
https://www.ncbi.nlm.nih.gov/pubmed/28553930
http://dx.doi.org/10.1038/oncsis.2017.40