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Spatial regulation of a common precursor from two distinct genes generates metabolite diversity

In secondary metabolite biosynthesis, core synthetic genes such as polyketide synthase genes usually encode proteins that generate various backbone precursors. These precursors are modified by other tailoring enzymes to yield a large variety of different secondary metabolites. The number of core syn...

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Detalles Bibliográficos
Autores principales: Guo, Chun-Jun, Sun, Wei-Wen, Bruno, Kenneth S., Oakley, Berl R., Keller, Nancy P., Wang, Clay C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523082/
https://www.ncbi.nlm.nih.gov/pubmed/28791090
http://dx.doi.org/10.1039/c5sc01058f