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The small heat-shock proteins IbpA and IbpB reduce the stress load of recombinant Escherichia coli and delay degradation of inclusion bodies

BACKGROUND: The permanently impaired protein folding during recombinant protein production resembles the stress encountered at extreme temperatures, under which condition the putative holding chaperones, IbpA/IbpB, play an important role. We evaluated the impact of ibpAB deletion or overexpression o...

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Detalles Bibliográficos
Autores principales: LeThanh, Ha, Neubauer, Peter, Hoffmann, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC552319/
https://www.ncbi.nlm.nih.gov/pubmed/15707488
http://dx.doi.org/10.1186/1475-2859-4-6