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Human APP Gene Expression Alters Active Zone Distribution and Spontaneous Neurotransmitter Release at the Drosophila Larval Neuromuscular Junction

This study provides further insight into the molecular mechanisms that control neurotransmitter release. Experiments were performed on larval neuromuscular junctions of transgenic Drosophila melanogaster lines with different levels of human amyloid precursor protein (APP) production. To express huma...

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Detalles Bibliográficos
Autores principales: Saburova, Ekaterina A., Vasiliev, Alexander N., Kravtsova, Violetta V., Ryabova, Elena V., Zefirov, Andrey L., Bolshakova, Olga I., Sarantseva, Svetlana V., Krivoi, Igor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523229/
https://www.ncbi.nlm.nih.gov/pubmed/28770114
http://dx.doi.org/10.1155/2017/9202584