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Plumbagin Alleviates Capillarization of Hepatic Sinusoids In Vitro by Downregulating ET-1, VEGF, LN, and Type IV Collagen

Critical roles for liver sinusoidal endothelial cells (LSECs) in liver fibrosis have been demonstrated, while little is known regarding the underlying molecular mechanisms of drugs delivered to the LSECs. Our previous study revealed that plumbagin plays an antifibrotic role in liver fibrosis. In thi...

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Detalles Bibliográficos
Autores principales: Li, Guiyu, Peng, Yue, Zhao, Tiejian, Lin, Jiyong, Duan, Xuelin, Wei, Yanfei, Ma, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523349/
https://www.ncbi.nlm.nih.gov/pubmed/28770223
http://dx.doi.org/10.1155/2017/5603216