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Plumbagin Alleviates Capillarization of Hepatic Sinusoids In Vitro by Downregulating ET-1, VEGF, LN, and Type IV Collagen
Critical roles for liver sinusoidal endothelial cells (LSECs) in liver fibrosis have been demonstrated, while little is known regarding the underlying molecular mechanisms of drugs delivered to the LSECs. Our previous study revealed that plumbagin plays an antifibrotic role in liver fibrosis. In thi...
Autores principales: | Li, Guiyu, Peng, Yue, Zhao, Tiejian, Lin, Jiyong, Duan, Xuelin, Wei, Yanfei, Ma, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523349/ https://www.ncbi.nlm.nih.gov/pubmed/28770223 http://dx.doi.org/10.1155/2017/5603216 |
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