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PEGylated Curcumin Derivative Attenuates Hepatic Steatosis via CREB/PPAR-γ/CD36 Pathway

Curcumin has the potential to cure dyslipidemia and nonalcoholic fatty liver disease (NAFLD). However, its therapeutic effects are curbed by poor bioavailability. Our previous work has shown that modification of curcumin with polyethylene glycol (PEG) improves blood concentration and tissue distribu...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Cheng, Fei, Luo, Yuxuan, Zhan, Zhu, Hu, Peng, Ren, Hong, Tang, Huadong, Peng, Mingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523402/
https://www.ncbi.nlm.nih.gov/pubmed/28770225
http://dx.doi.org/10.1155/2017/8234507