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Ocular Adverse Effects of Intravitreal Bevacizumab Are Potentiated by Intermittent Hypoxia in a Rat Model of Oxygen-Induced Retinopathy

Intravitreal bevacizumab (Avastin) use in preterm infants with retinopathy of prematurity is associated with severe neurological disabilities, suggesting vascular leakage. We examined the hypothesis that intermittent hypoxia (IH) potentiates intravitreal Avastin leakage. Neonatal rats at birth were...

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Detalles Bibliográficos
Autores principales: Tan, Jeffrey J., Cai, Charles L., Shrier, Eric M., McNally, Lois, Lazzaro, Douglas R., Aranda, Jacob V., Beharry, Kay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523466/
https://www.ncbi.nlm.nih.gov/pubmed/28770109
http://dx.doi.org/10.1155/2017/4353129