Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway

OBJECTIVE: Curcumin (diferuloylmethane) is a yellow-colored polyphenol with antiproliferative and proapoptotic activities to various types of cancer cells. This study explored the mechanism by which curcumin induces p53-null hepatoma cell apoptosis. RESULTS: AKT, FOXO1, and FOXO3 proteins were downr...

Descripción completa

Detalles Bibliográficos
Autores principales: Liou, An-Ting, Chen, Mei-Fang, Yang, Chu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523542/
https://www.ncbi.nlm.nih.gov/pubmed/28769986
http://dx.doi.org/10.1155/2017/4063865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523542/
https://www.ncbi.nlm.nih.gov/pubmed/28769986
http://dx.doi.org/10.1155/2017/4063865

Ejemplares similares