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Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway

OBJECTIVE: Curcumin (diferuloylmethane) is a yellow-colored polyphenol with antiproliferative and proapoptotic activities to various types of cancer cells. This study explored the mechanism by which curcumin induces p53-null hepatoma cell apoptosis. RESULTS: AKT, FOXO1, and FOXO3 proteins were downr...

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Detalles Bibliográficos
Autores principales:	Liou, An-Ting, Chen, Mei-Fang, Yang, Chu-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523542/ https://www.ncbi.nlm.nih.gov/pubmed/28769986 http://dx.doi.org/10.1155/2017/4063865

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