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Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy

Therapies based on transplantation of mesenchymal stromal cells (MSC) hold promise for the management of inflammatory disorders. In chronic Chagas disease cardiomyopathy (CCC), caused by chronic infection with Trypanosoma cruzi, the exacerbated immune response plays a critical pathophysiological rol...

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Detalles Bibliográficos
Autores principales: Souza, Bruno Solano de Freitas, da Silva, Kátia Nunes, Silva, Daniela Nascimento, Rocha, Vinícius Pinto Costa, Paredes, Bruno Diaz, Azevedo, Carine Machado, Nonaka, Carolina Kymie, Carvalho, Gisele Batista, Vasconcelos, Juliana Fraga, dos Santos, Ricardo Ribeiro, Soares, Milena Botelho Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523546/
https://www.ncbi.nlm.nih.gov/pubmed/28769980
http://dx.doi.org/10.1155/2017/3282656