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Mismatch Repair Deficiency as a Predictive Biomarker for Immunotherapy Efficacy

Immunotherapy has revolutionized cancer treatment. Immune-checkpoint inhibitors, on balance, showed a favorable efficacy/toxicity profile with durable response in different cancer types. No predictive biomarker has been validated thus far to select patients who would benefit from therapy. Among the...

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Detalles Bibliográficos
Autores principales: Viale, Giulia, Trapani, Dario, Curigliano, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523547/
https://www.ncbi.nlm.nih.gov/pubmed/28770222
http://dx.doi.org/10.1155/2017/4719194