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Induction of Lipin1 by ROS-Dependent SREBP-2 Activation

Lipin1 was identified as a phosphatidate phosphatase enzyme, and it plays a key role in lipid metabolism. Since free radicals contribute to metabolic diseases in the liver, this study investigated the effects of free radicals on the regulation of Lipin1 expression in Huh7 and AML12 cells. Hydrogen p...

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Detalles Bibliográficos
Autores principales: Seo, Kyuhwa, Shin, Sang Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523558/
https://www.ncbi.nlm.nih.gov/pubmed/28744353
http://dx.doi.org/10.5487/TR.2017.33.3.219