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Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

TCR stimulation by peptide–MHC complexes on APCs requires precise reorganization of molecules into the area of cellular contact to form an immunological synapse from where T cell signaling is initiated. Caveolin (Cav)1, a widely expressed transmembrane protein, is involved in the regulation of membr...

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Detalles Bibliográficos
Autores principales: Borger, Jessica G., Morrison, Vicky L., Filby, Andrew, Garcia, Celine, Uotila, Liisa M., Simbari, Fabio, Fagerholm, Susanna C., Zamoyska, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523581/
https://www.ncbi.nlm.nih.gov/pubmed/28637901
http://dx.doi.org/10.4049/jimmunol.1700431