Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

BACKGROUND: Marfan syndrome (MFS) is caused by mutations in the gene encoding fibrillin‐1 (FBN1); however, the mechanisms through which fibrillin‐1 deficiency causes MFS‐associated aortopathy are uncertain. Recently, attention was focused on the hypothesis that MFS‐associated aortopathy is caused by...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Hao, Hu, Jie Hong, Angelov, Stoyan N., Fox, Kate, Yan, James, Enstrom, Rachel, Smith, Alexandra, Dichek, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523644/
https://www.ncbi.nlm.nih.gov/pubmed/28119285
http://dx.doi.org/10.1161/JAHA.116.004968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523644/
https://www.ncbi.nlm.nih.gov/pubmed/28119285
http://dx.doi.org/10.1161/JAHA.116.004968

Ejemplares similares