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The IDO–AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection

In infectious diseases, the enzyme indoleamine 2,3 dioxygenase-1 (IDO1) that catalyzes the tryptophan (Trp) degradation along the kynurenines (Kyn) pathway has two main functions, the control of pathogen growth by reducing available Trp and immune regulation mediated by the Kyn-mediated expansion of...

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Detalles Bibliográficos
Autores principales: de Araújo, Eliseu Frank, Feriotti, Claudia, Galdino, Nayane Alves de Lima, Preite, Nycolas Willian, Calich, Vera Lúcia Garcia, Loures, Flávio Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523665/
https://www.ncbi.nlm.nih.gov/pubmed/28791025
http://dx.doi.org/10.3389/fimmu.2017.00880