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The IDO–AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection
In infectious diseases, the enzyme indoleamine 2,3 dioxygenase-1 (IDO1) that catalyzes the tryptophan (Trp) degradation along the kynurenines (Kyn) pathway has two main functions, the control of pathogen growth by reducing available Trp and immune regulation mediated by the Kyn-mediated expansion of...
Autores principales: | de Araújo, Eliseu Frank, Feriotti, Claudia, Galdino, Nayane Alves de Lima, Preite, Nycolas Willian, Calich, Vera Lúcia Garcia, Loures, Flávio Vieira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523665/ https://www.ncbi.nlm.nih.gov/pubmed/28791025 http://dx.doi.org/10.3389/fimmu.2017.00880 |
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