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Vinexin β Ablation Inhibits Atherosclerosis in Apolipoprotein E–Deficient Mice by Inactivating the Akt–Nuclear Factor κB Inflammatory Axis

BACKGROUND: Vinexin β is a novel adaptor protein that regulates cellular adhesion, cytoskeletal reorganization, signal transduction, and transcription; however, the exact role that vinexin β plays in atherosclerosis remains unknown. METHODS AND RESULTS: Immunoblot analysis showed that vinexin β expr...

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Detalles Bibliográficos
Autores principales: Guan, Hongjing, Cheng, Wen‐Lin, Guo, Junhong, Chao, Meng‐Lin, Zhang, Yan, Gong, Jun, Zhu, Xue‐Yong, She, Zhi‐Gang, Huang, Zan, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523760/
https://www.ncbi.nlm.nih.gov/pubmed/28209562
http://dx.doi.org/10.1161/JAHA.116.004585