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Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion

BACKGROUND: Cardiomyocyte‐specific transgenic mice overexpressing S100A6, a member of the family of EF‐hand calcium‐binding proteins, develop less cardiac hypertrophy, interstitial fibrosis, and myocyte apoptosis after permanent coronary ligation, findings that support S100A6 as a potential therapeu...

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Detalles Bibliográficos
Autores principales: Mofid, Azadeh, Newman, Nadav S., Lee, Paul J. H., Abbasi, Cynthia, Matkar, Pratiek N., Rudenko, Dmitriy, Kuliszewski, Michael A., Chen, Hao H., Afrasiabi, Kolsoom, Tsoporis, James N., Gramolini, Anthony O., Connelly, Kim A., Parker, Thomas G., Leong‐Poi, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523770/
https://www.ncbi.nlm.nih.gov/pubmed/28174168
http://dx.doi.org/10.1161/JAHA.116.004738