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Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion
BACKGROUND: Cardiomyocyte‐specific transgenic mice overexpressing S100A6, a member of the family of EF‐hand calcium‐binding proteins, develop less cardiac hypertrophy, interstitial fibrosis, and myocyte apoptosis after permanent coronary ligation, findings that support S100A6 as a potential therapeu...
Autores principales: | Mofid, Azadeh, Newman, Nadav S., Lee, Paul J. H., Abbasi, Cynthia, Matkar, Pratiek N., Rudenko, Dmitriy, Kuliszewski, Michael A., Chen, Hao H., Afrasiabi, Kolsoom, Tsoporis, James N., Gramolini, Anthony O., Connelly, Kim A., Parker, Thomas G., Leong‐Poi, Howard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523770/ https://www.ncbi.nlm.nih.gov/pubmed/28174168 http://dx.doi.org/10.1161/JAHA.116.004738 |
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