Dimerized Domain V of Beta2-Glycoprotein I Is Sufficient to Upregulate Procoagulant Activity in PMA-Treated U937 Monocytes and Require Intact Residues in Two Phospholipid-Binding Loops

Upregulation of the procoagulant activity of monocytes by antibodies to beta2-glycoprotein I (β2GPI) is one of the mechanisms contributing to thrombosis in antiphospholipid syndrome. Current knowledge about receptors responsible for the upregulation of procoagulant activity by β2GPI/anti-β2GPI compl...

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Detalles Bibliográficos
Autores principales: Kolyada, Alexey, Barrios, David A., Beglova, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523967/
https://www.ncbi.nlm.nih.gov/pubmed/28748111
http://dx.doi.org/10.3390/antib6020008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523967/
https://www.ncbi.nlm.nih.gov/pubmed/28748111
http://dx.doi.org/10.3390/antib6020008

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