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Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin–avidin-specific binding

Developing magnetic resonance imaging (MRI) contrast agents with high relaxivity and specificity was essential to increase MRI diagnostic sensitivity and accuracy. In this study, the MRI contrast agent, vascular endothelial growth factor receptor (VEGFR)-targeted poly (l-lysine) (PLL)-diethylene tri...

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Detalles Bibliográficos
Autores principales: Liu, Yongjun, Wu, Xiaoyun, Sun, Xiaohe, Wang, Dan, Zhong, Ying, Jiang, Dandan, Wang, Tianqi, Yu, Dexin, Zhang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523973/
https://www.ncbi.nlm.nih.gov/pubmed/28765707
http://dx.doi.org/10.2147/IJN.S131878