Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction

BACKGROUND: Endothelial dysfunction contributes significantly to the development of vascular diseases. However, a therapy able to reduce this derangement still needs to be identified. We evaluated the effects of pharmacological inhibition of Rac1, a small GTPase protein promoting oxidative stress, i...

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Detalles Bibliográficos
Autores principales: Carrizzo, Albino, Vecchione, Carmine, Damato, Antonio, di Nonno, Flavio, Ambrosio, Mariateresa, Pompeo, Franco, Cappello, Enrico, Capocci, Luca, Peruzzi, Mariangela, Valenti, Valentina, Biondi‐Zoccai, Giuseppe, Marullo, Antonino G. M., Palmerio, Silvia, Carnevale, Roberto, Spinelli, Chiara C., Puca, Annibale A., Rubattu, Speranza, Volpe, Massimo, Sadoshima, Junichi, Frati, Giacomo, Sciarretta, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524008/
https://www.ncbi.nlm.nih.gov/pubmed/28246076
http://dx.doi.org/10.1161/JAHA.116.004746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524008/
https://www.ncbi.nlm.nih.gov/pubmed/28246076
http://dx.doi.org/10.1161/JAHA.116.004746

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