Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

BACKGROUND: The cardiac microvascular system ischemia/reperfusion injury following percutaneous coronary intervention is a clinical thorny problem. This study explores the mechanisms by which ischemia/reperfusion injury induces cardiac microcirculation collapse. METHODS AND RESULTS: In wild‐type mic...

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Detalles Bibliográficos
Autores principales: Zhou, Hao, Hu, Shunying, Jin, Qinhua, Shi, Chen, Zhang, Ying, Zhu, Pingjun, Ma, Qiang, Tian, Feng, Chen, Yundai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524036/
https://www.ncbi.nlm.nih.gov/pubmed/28288978
http://dx.doi.org/10.1161/JAHA.116.005328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524036/
https://www.ncbi.nlm.nih.gov/pubmed/28288978
http://dx.doi.org/10.1161/JAHA.116.005328

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