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Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

BACKGROUND: The cardiac microvascular system ischemia/reperfusion injury following percutaneous coronary intervention is a clinical thorny problem. This study explores the mechanisms by which ischemia/reperfusion injury induces cardiac microcirculation collapse. METHODS AND RESULTS: In wild‐type mic...

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Detalles Bibliográficos
Autores principales:	Zhou, Hao, Hu, Shunying, Jin, Qinhua, Shi, Chen, Zhang, Ying, Zhu, Pingjun, Ma, Qiang, Tian, Feng, Chen, Yundai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524036/ https://www.ncbi.nlm.nih.gov/pubmed/28288978 http://dx.doi.org/10.1161/JAHA.116.005328

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