Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross talks

Macrophage stimulation with interferon-γ (IFN-γ) and interleukin 4 (IL-4) triggers distinct and opposing activation programs. During mixed infections or cancer macrophages are often exposed to both cytokines, but how these two programs influence each other remains unclear. We found that IFN-γ and IL...

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Detalles Bibliográficos
Autores principales: Piccolo, Viviana, Curina, Alessia, Genua, Marco, Ghisletti, Serena, Simonatto, Marta, Sabò, Arianna, Amati, Bruno, Ostuni, Renato, Natoli, Gioacchino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524187/
https://www.ncbi.nlm.nih.gov/pubmed/28288101
http://dx.doi.org/10.1038/ni.3710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524187/
https://www.ncbi.nlm.nih.gov/pubmed/28288101
http://dx.doi.org/10.1038/ni.3710

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