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Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H(2)S system: Role of oxidative stress and endoplasmic reticulum stress

Neonatal hypoxic-ischemic (HI) injury is a major cause of neonatal death and neurological dysfunction. H(2)S has been shown to protect against hypoxia-induced injury and apoptosis of neurons. L-Cysteine is catalyzed by cystathionine-β-synthase (CBS) in the brain and sequentially produces endogenous...

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Detalles Bibliográficos
Autores principales: Liu, Song, Xin, Danqing, Wang, Lingxiao, Zhang, Tiantian, Bai, Xuemei, Li, Tong, Xie, Yunkai, Xue, Hao, Bo, Shishi, Liu, Dexiang, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524226/
https://www.ncbi.nlm.nih.gov/pubmed/28735240
http://dx.doi.org/10.1016/j.redox.2017.06.007