Species A rotavirus NSP3 acquires its translation inhibitory function prior to stable dimer formation

Species A rotavirus non-structural protein 3 (NSP3) is a translational regulator that inhibits or, under some conditions, enhances host cell translation. NSP3 binds to the translation initiation factor eIF4G1 and evicts poly-(A) binding protein (PABP) from eIF4G1, thus inhibiting translation of poly...

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Detalles Bibliográficos
Autores principales: Contreras-Treviño, Hugo I., Reyna-Rosas, Edgar, León-Rodríguez, Renato, Ruiz-Ordaz, Blanca H., Dinkova, Tzvetanka D., Cevallos, Ana M., Padilla-Noriega, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524322/
https://www.ncbi.nlm.nih.gov/pubmed/28738064
http://dx.doi.org/10.1371/journal.pone.0181871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524322/
https://www.ncbi.nlm.nih.gov/pubmed/28738064
http://dx.doi.org/10.1371/journal.pone.0181871

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