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Human Tamm-Horsfall protein, a renal specific protein, serves as a cofactor in complement 3b degradation
Tamm-Horsfall protein (THP) is an abundant urinary protein of renal origin. We hypothesize that THP can act as an inhibitor of complement since THP binds complement 1q (C1q) of the classical complement pathway, inhibits activation of this pathway, and is important in decreasing renal ischemia-reperf...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524369/ https://www.ncbi.nlm.nih.gov/pubmed/28742158 http://dx.doi.org/10.1371/journal.pone.0181857 |