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Variants of ACAN are associated with severity of lumbar disc herniation in patients with chronic low back pain

INTRODUCTION: Disc herniation is a complex spinal disorder associated with disability and high healthcare cost. Lumbar disc herniation is strongly associated with disc degeneration. Candidate genes of the aggrecan metabolic pathway may associate with the severity of lumbar disc herniation. OBJECTIVE...

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Detalles Bibliográficos
Autores principales: Perera, Romain Shanil, Dissanayake, Poruwalage Harsha, Senarath, Upul, Wijayaratne, Lalith Sirimevan, Karunanayake, Aranjan Lional, Dissanayake, Vajira Harshadeva Weerabaddana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524386/
https://www.ncbi.nlm.nih.gov/pubmed/28742099
http://dx.doi.org/10.1371/journal.pone.0181580