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Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats

OBJECTIVE: To determine the effects of exogenous glucagon-like peptide-2 (GLP-2), with or without massive distal bowel resection, on adaptation of jejunal mucosa, enteric neurons, gut hormones and tissue reserves in rats. BACKGROUND: GLP-2 is a gut hormone known to be trophic for small bowel mucosa,...

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Detalles Bibliográficos
Autores principales: Lai, Sarah W., de Heuvel, Elaine, Wallace, Laurie E., Hartmann, Bolette, Holst, Jens J., Brindle, Mary E., Chelikani, Prasanth K., Sigalet, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524396/
https://www.ncbi.nlm.nih.gov/pubmed/28738080
http://dx.doi.org/10.1371/journal.pone.0181453