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Rolling Circle Mutagenesis of GST-mCherry to Understand Mutation, Gene Expression, and Regulation

Undergraduates are often familiar with textbook examples of human mutations that affect coding regions and the subsequent disorders, but they may struggle with understanding the implications of mutations in the regulatory regions of genes. We have designed a laboratory sequence that will allow stude...

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Detalles Bibliográficos
Autores principales: Cole, Jessica, Ferguson, Amanda, Segarra, Verónica A., Walsh, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524438/
https://www.ncbi.nlm.nih.gov/pubmed/28904643
http://dx.doi.org/10.1128/jmbe.v18i1.1201