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Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
Hypoxia regulates autophagy and nucleotide-binding oligomerization domain receptor, pyrin domain containing (NLRP)3, two innate immune mechanisms linked by mutual regulation and associated to IBD. Here we show that hypoxia ameliorates inflammation during the development of colitis by modulating auto...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524634/ https://www.ncbi.nlm.nih.gov/pubmed/28740109 http://dx.doi.org/10.1038/s41467-017-00213-3 |