DNA end resection requires constitutive sumoylation of CtIP by CBX4

DNA breaks are complex DNA lesions that can be repaired by two alternative mechanisms: non-homologous end-joining and homologous recombination. The decision between them depends on the activation of the DNA resection machinery, which blocks non-homologous end-joining and stimulates recombination. On...

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Detalles Bibliográficos
Autores principales: Soria-Bretones, Isabel, Cepeda-García, Cristina, Checa-Rodriguez, Cintia, Heyer, Vincent, Reina-San-Martin, Bernardo, Soutoglou, Evi, Huertas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524638/
https://www.ncbi.nlm.nih.gov/pubmed/28740167
http://dx.doi.org/10.1038/s41467-017-00183-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524638/
https://www.ncbi.nlm.nih.gov/pubmed/28740167
http://dx.doi.org/10.1038/s41467-017-00183-6

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