Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

Muscle-invasive bladder cancer (MIBC) is an aggressive disease with limited therapeutic options. Although immunotherapies are approved for MIBC, the majority of patients fail to respond, suggesting existence of complementary immune evasion mechanisms. Here, we report that the PPARγ/RXRα pathway cons...

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Detalles Bibliográficos
Autores principales: Korpal, Manav, Puyang, Xiaoling, Jeremy Wu, Zhenhua, Seiler, Roland, Furman, Craig, Oo, Htoo Zarni, Seiler, Michael, Irwin, Sean, Subramanian, Vanitha, Julie Joshi, Jaya, Wang, Chris K., Rimkunas, Victoria, Tortora, Davide, Yang, Hua, Kumar, Namita, Kuznetsov, Galina, Matijevic, Mark, Chow, Jesse, Kumar, Pavan, Zou, Jian, Feala, Jacob, Corson, Laura, Henry, Ryan, Selvaraj, Anand, Davis, Allison, Bloudoff, Kristjan, Douglas, James, Kiss, Bernhard, Roberts, Morgan, Fazli, Ladan, Black, Peter C., Fekkes, Peter, Smith, Peter G., Warmuth, Markus, Yu, Lihua, Hao, Ming-Hong, Larsen, Nicholas, Daugaard, Mads, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524640/
https://www.ncbi.nlm.nih.gov/pubmed/28740126
http://dx.doi.org/10.1038/s41467-017-00147-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524640/
https://www.ncbi.nlm.nih.gov/pubmed/28740126
http://dx.doi.org/10.1038/s41467-017-00147-w

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