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PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens

Pharmacological and functional genomic screens play an essential role in the discovery and characterization of therapeutic targets and associated pharmacological inhibitors. Although these screens affect thousands of gene products, the typical readout is based on low complexity rather than genome-wi...

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Detalles Bibliográficos
Autores principales: Bush, Erin C., Ray, Forest, Alvarez, Mariano J., Realubit, Ronald, Li, Hai, Karan, Charles, Califano, Andrea, Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524642/
https://www.ncbi.nlm.nih.gov/pubmed/28740083
http://dx.doi.org/10.1038/s41467-017-00136-z