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PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
Pharmacological and functional genomic screens play an essential role in the discovery and characterization of therapeutic targets and associated pharmacological inhibitors. Although these screens affect thousands of gene products, the typical readout is based on low complexity rather than genome-wi...
Autores principales: | Bush, Erin C., Ray, Forest, Alvarez, Mariano J., Realubit, Ronald, Li, Hai, Karan, Charles, Califano, Andrea, Sims, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524642/ https://www.ncbi.nlm.nih.gov/pubmed/28740083 http://dx.doi.org/10.1038/s41467-017-00136-z |
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