Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation

The peripheral membrane proto-oncogene Src family protein tyrosine kinases relay growth factor signals to the cytoplasm of mammalian cells. We unravel the spatial cycles of solubilisation, trapping on perinuclear membrane compartments and vesicular transport that counter entropic equilibration to en...

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Detalles Bibliográficos
Autores principales: Konitsiotis, Antonios D., Roßmannek, Lisaweta, Stanoev, Angel, Schmick, Malte, Bastiaens, Philippe I. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524651/
https://www.ncbi.nlm.nih.gov/pubmed/28740133
http://dx.doi.org/10.1038/s41467-017-00116-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524651/
https://www.ncbi.nlm.nih.gov/pubmed/28740133
http://dx.doi.org/10.1038/s41467-017-00116-3

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