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Novel drug targets for Mycobacterium tuberculosis: 2-heterostyrylbenzimidazoles as inhibitors of cell wall protein synthesis

BACKGROUND: Multi drug-resistant and mycobacterial infections are a major public health challenge, leading to high mortality and socioeconomic burdens through worldwide. Novel therapeutics are necessary to treat the drug resistant strains, since no new chemical entities are emerged in the last four...

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Detalles Bibliográficos
Autores principales: Anguru, Mohana Rao, Taduri, Ashok Kumar, Bhoomireddy, Rama Devi, Jojula, Malathi, Gunda, Shravan Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524660/
https://www.ncbi.nlm.nih.gov/pubmed/29086847
http://dx.doi.org/10.1186/s13065-017-0295-z