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Exploring the binding sites and proton diffusion on insulin amyloid fibril surfaces by naphthol-based photoacid fluorescence and molecular simulations

The diffusion of protons along biological surfaces and the interaction of biological structures with water are fundamental areas of interest in biology and chemistry. Here, we examine the surface of insulin amyloid fibrils and follow the binding of small molecules (photoacids) that differ according...

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Detalles Bibliográficos
Autores principales: Amdursky, Nadav, Rashid, M. Harunur, Stevens, Molly M., Yarovsky, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524688/
https://www.ncbi.nlm.nih.gov/pubmed/28740173
http://dx.doi.org/10.1038/s41598-017-06030-4