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Exploring the binding sites and proton diffusion on insulin amyloid fibril surfaces by naphthol-based photoacid fluorescence and molecular simulations
The diffusion of protons along biological surfaces and the interaction of biological structures with water are fundamental areas of interest in biology and chemistry. Here, we examine the surface of insulin amyloid fibrils and follow the binding of small molecules (photoacids) that differ according...
Autores principales: | Amdursky, Nadav, Rashid, M. Harunur, Stevens, Molly M., Yarovsky, Irene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524688/ https://www.ncbi.nlm.nih.gov/pubmed/28740173 http://dx.doi.org/10.1038/s41598-017-06030-4 |
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