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A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP
Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report, the deve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524698/ https://www.ncbi.nlm.nih.gov/pubmed/28740152 http://dx.doi.org/10.1038/s41598-017-06432-4 |