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A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP

Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report, the deve...

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Detalles Bibliográficos
Autores principales: Zhu, Yingmin, Mei, Fang, Luo, Pei, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524698/
https://www.ncbi.nlm.nih.gov/pubmed/28740152
http://dx.doi.org/10.1038/s41598-017-06432-4