Cargando…
A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP
Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report, the deve...
Autores principales: | Zhu, Yingmin, Mei, Fang, Luo, Pei, Cheng, Xiaodong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524698/ https://www.ncbi.nlm.nih.gov/pubmed/28740152 http://dx.doi.org/10.1038/s41598-017-06432-4 |
Ejemplares similares
-
Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis
por: Ni, Zhuofu, et al.
Publicado: (2021) -
Structural Analyses of a Constitutively Active Mutant of Exchange Protein Directly Activated by cAMP
por: White, Mark A., et al.
Publicado: (2012) -
Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets
por: Wang, Pingyuan, et al.
Publicado: (2017) -
Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative Structural Biology
por: White, Mark Andrew, et al.
Publicado: (2019) -
Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics
por: Banerjee, Upasana, et al.
Publicado: (2015)