Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies

Despite doxorubicin being commonly used in chemotherapy there still remain significant holes in our knowledge regarding its delivery efficacy and an observed resistance mechanism that is postulated to involve the cell membrane. One possible mechanism is the efflux by protein P-gp, which is found pre...

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Detalles Bibliográficos
Autores principales: Alves, Ana Catarina, Magarkar, Aniket, Horta, Miguel, Lima, Jose L. F. C., Bunker, Alex, Nunes, Cláudia, Reis, Salette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524714/
https://www.ncbi.nlm.nih.gov/pubmed/28740256
http://dx.doi.org/10.1038/s41598-017-06445-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524714/
https://www.ncbi.nlm.nih.gov/pubmed/28740256
http://dx.doi.org/10.1038/s41598-017-06445-z

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