Selective Inhibition of Janus Kinase 3 Has No Impact on Infarct Size or Neurobehavioral Outcomes in Permanent Ischemic Stroke in Mice

Janus kinase 3 (JAK3) is associated with the common gamma chain of several interleukin (IL) receptors essential to inflammatory signaling. To study the potential role of JAK3 in stroke-induced neuroinflammation, we subjected mice to permanent middle cerebral artery occlusion and investigated the eff...

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Detalles Bibliográficos
Autores principales: DeMars, Kelly M., Pacheco, Sean C., Yang, Changjun, Siwarski, David M., Candelario-Jalil, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524742/
https://www.ncbi.nlm.nih.gov/pubmed/28790974
http://dx.doi.org/10.3389/fneur.2017.00363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524742/
https://www.ncbi.nlm.nih.gov/pubmed/28790974
http://dx.doi.org/10.3389/fneur.2017.00363

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