The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte

An increase in intraovarian reactive oxygen species (ROS) has long been implicated in the decline in oocyte quality associated with maternal ageing. Oxidative stress (OS)-induced lipid peroxidation and the consequent generation of highly electrophilic aldehydes, such as 4-hydroxynonenal (4-HNE), rep...

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Detalles Bibliográficos
Autores principales: Mihalas, Bettina P., De Iuliis, Geoffry N., Redgrove, Kate A., McLaughlin, Eileen A., Nixon, Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524799/
https://www.ncbi.nlm.nih.gov/pubmed/28740075
http://dx.doi.org/10.1038/s41598-017-06372-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524799/
https://www.ncbi.nlm.nih.gov/pubmed/28740075
http://dx.doi.org/10.1038/s41598-017-06372-z

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