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Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks

Induced pluripotent stem cells (iPSCs) are similar to embryonic stem cells and can be generated from somatic cells. We have generated episomal plasmid-based and integration-free iPSCs (E-iPSCs) from human fetal foreskin fibroblast cells (HFF1). We used an E-iPSC-line to model hepatogenesis in vitro....

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Detalles Bibliográficos
Autores principales: Matz, Peggy, Wruck, Wasco, Fauler, Beatrix, Herebian, Diran, Mielke, Thorsten, Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524812/
https://www.ncbi.nlm.nih.gov/pubmed/28740077
http://dx.doi.org/10.1038/s41598-017-06546-9