Absence of Tissue Inhibitor of Metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption

Tissue inhibitor of metalloproteases (TIMPs) are inhibitors of matrix metalloproteinases (MMPs) that regulate tissue extracellular matrix (ECM) turnover. TIMP4 is highly expressed in adipose tissue, its levels are further elevated following high-fat diet, but its role in obesity is unknown. Eight-we...

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Detalles Bibliográficos
Autores principales: Sakamuri, Siva S. V. P., Watts, Russell, Takawale, Abhijit, Wang, Xiuhua, Hernandez-Anzaldo, Samuel, Bahitham, Wesam, Fernandez-Patron, Carlos, Lehner, Richard, Kassiri, Zamaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524827/
https://www.ncbi.nlm.nih.gov/pubmed/28740132
http://dx.doi.org/10.1038/s41598-017-05951-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524827/
https://www.ncbi.nlm.nih.gov/pubmed/28740132
http://dx.doi.org/10.1038/s41598-017-05951-4

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